Research Library · Compound Guide
CJC-1295 (No DAC / Modified GRF 1-29): Research Overview & Molecular Profile
CJC-1295 without DAC - also referred to in the literature as Modified GRF (1-29) - is a synthetic peptide derivative of growth-hormone-releasing hormone (GHRH). It represents a modified analog of the first 29 amino acids of GHRH. The "No DAC" designation distinguishes it from the DAC (Drug Affinity Complex) conjugated version: unlike CJC-1295 DAC, the No-DAC form does not carry the DAC moiety and, in research characterization, exhibits a shorter circulating half-life. It is supplied as a lyophilized research powder for laboratory study. At AurexBioLabs, CJC-1295 (No DAC) is supplied strictly as a research compound with third-party testing and a Certificate of Analysis on every batch.
For Research Use Only. Not for human or veterinary use. Not a drug, food, or cosmetic. This page is educational reference material for qualified researchers and contains no medical advice, dosing, or health claims.
CJC-1295 (No DAC) Molecular Profile
| Compound type | Synthetic GHRH analog / peptide (Modified GRF 1-29) |
|---|---|
| Molecular formula | C152H252N44O42 |
| Molecular weight | ~3367.9 g/mol |
| CAS number | 446036-97-1 |
| Also known as | Modified GRF (1-29), CJC-1295 DAC-free, GHRH (1-29) analog |
| Physical form | Lyophilized white powder |
Research Context
In preclinical literature, CJC-1295 (No DAC) is described as a growth-hormone-releasing hormone analog studied in laboratory models of the GHRH signaling pathway. A frequent focus of published characterization is the structural and pharmacokinetic difference between the No-DAC and DAC-conjugated forms - specifically the effect of the DAC moiety on half-life in research models. CJC-1295 has not been approved by the FDA for any human or veterinary use. Referenced findings are limited to laboratory research; consult primary sources for detail.
Handling & Laboratory Considerations
Storage
Lyophilized material stored frozen, protected from light.
Reconstitution (research context)
Bacteriostatic or sterile water per protocol; refrigerate reconstituted solution.
Stability
Avoid repeated freeze-thaw; protect from heat and light.
Quality & Verification at AurexBioLabs
Every batch of CJC-1295 (No DAC) is third-party HPLC and mass-spec verified, with a Certificate of Analysis. Check your lot number at our verification page.
Frequently Asked Questions
The DAC (Drug Affinity Complex) version carries an added moiety associated with a longer circulating half-life in research models; the No DAC form (Modified GRF 1-29) does not, and shows a shorter half-life in characterization studies.
Approximately 3367.9 g/mol.
446036-97-1.
Yes - the two names refer to the same DAC-free GHRH analog.
Yes - HPLC and mass-spec verified with a COA per batch.
Next Steps
Verification & catalog
For Research Use Only. Not for human or veterinary use. Not a drug, food, or cosmetic. This page is educational reference material for qualified researchers and contains no medical advice, dosing, or health claims.
CJC-1295 (No DAC) is sold for laboratory research use only. Not for human or veterinary use, diagnostic, or therapeutic purposes.